Before he played Captain America, Chris Evans also appeared as Johnny Storm/The Human Torch in two Fantastic Four movies. Brolin's Deadpool co-star Ryan Reynolds was also Hal Jordan in the Green Lantern movie, while Halle Berry has played both hero and villain as Storm and Catwoman respectively.
So here are ten more actors who have played different comic book characters on screen.
1. Ben Affleck
Before he was the Dark Knight, Affleck was Daredevil in the 2003 big screen version.
2. Angela Bassett
Appearing in Green Lantern as Amanda Waller, Bassett is taking the role of Queen Mother Ramonda in the upcoming Black Panther film.
3. Willem Dafoe
Dafoe played Norman Osborn/Green Goblin in the Sam Raimi Spider-Man films; he will be playing Atlantean advisor Nuidis Vulko in Justice League and Aquaman
4. Laurence Fishburne
Known for playing Perry White in the DC Extended Universe films, Fishburne provides the voice of the titular character in Fantastic Four: Rise Of The SIlver Surfer.
5. Tommy Lee Jones
From villain to hero: Jones played Harvey Dent/Two-Face in Joel Schumacher's camptastic Batman Forever, before taking the role of Colonel Chester Phillips in Captain America: The First Avenger
6. Michael B. Jordan
Jordan is one of the few bearable things in Josh Trank's disastrous Fantastic Four reboot; he will appear in Black Panther as the wonderfully named Erik Killmonger.
7. Michael Keaton
From hero to villain: Keaton played the lead role in Tim Burton's two Batman movies, and will play Adrian Toomes/The Vulture in the upcoming Spider-Man: Homecoming
8. Nicole Kidman
Kidman appeared with Tommy Lee Jones in Batman Forever as Dr. Chase Meridian; she will also play Queen Atlanna in the upcoming Aquaman film.
9. J.K. Simmons
Oscar-winner Simmons will be swapping The Daily Bugle for the Gotham City Police Department, going from playing J. Jonah Jameson in the Sam Raimi Spider-Man films to Commissioner Gordon in Justice League.
10. Terence Stamp
Stamp played General Zod in Superman and Superman II (and also went on to be the voice of Jor-El in Smallville). He also played Elektra's mentor Stick in the 2005 Daredevil spin-off.
Bonus: Sylvester Stallone
Stallone played Judge Dredd in the 1995 film version of the 2000AD comic; he has a small role in Guardians Of The Galaxy Vol. 2 (but the character has not yet been revealed)